Asia Pacific Journal of Health Management <p>The Asia Pacific Journal of Health Management (APJHM) is a peer-reviewed journal for managers of organisations offering healthcare and aged care services. The APJHM aims to promote the discipline of health management throughout the region by facilitating the transfer of knowledge among readers by widening the evidence base for management practices.<br /><br />*Print 1(1);2006 - 5(1);2010 Online 4(2);2009 - current<br />*ISSN 2204-3136 (online); ISSN 1833-3818 (print)</p> en-US (Yaping Liu) (Yaping Liu) Sat, 08 Apr 2023 00:00:00 -0700 OJS 60 Determinants of intention to use Health Wristbands in India: Application of modified Technology Acceptance Model <p><strong>Objective</strong> – Post Covid-19, people are becoming more and more self-reliant in terms of basic health needs and moving towards technology enabled health products and services. Present study aims to analyse the factors affecting the intention to use health wristbands in India.</p> <p><strong>Design &amp; Setting</strong> – Current research is based technology acceptance model (TAM) constructs and used a structured questionnaire to collect data from 350 respondents from major cities of India. The data has been analysed using confirmatory factor analysis and partial least square-structural equation modelling (PLS-SEM) approach.</p> <p><strong>Results</strong> – The values of Cronbach alpha, composite reliability, and AVE highlights adequate level of reliability, construct validity, and discriminant validity of the data. Based on the output of structural model, the results indicate that perceived ease of use, perceived trust, and perceived security are major determinants of health wristbands in India. Further, the results provide weak evidence for the relation between perceived usefulness and intention to use health wristbands.</p> <p><strong>Conclusion – </strong>Current study contributes to the growing literature of TAM by incorporating additional factors along with conventional ones. The study conveys that Indian population possess higher intention to use health wristbands which are perceived to be easy to use, provides trustworthy and accurate information, and ensure data security and right of privacy to users.</p> Dr. Stafard Anthony, Dr. Krunal Soni, Dr. Rajesh Desai Copyright (c) Clinical Emergence of Extended Spectrum β-lactamases (ESBL) : A review <p><strong>Aim:</strong> Bacterial antibiotic resistance genes have a very high frequency of mutations. Strong selective pressure further accelerates the rate of antibiotic resistance genes mutation.&nbsp; &nbsp;Extended-spectrum β – lactamases (ESBLs) are plasmid-mediated enzymes that can hydrolyze and inactivate a broad range of β – lactams, including third-generation cephalosporins, penicillins, and aztreonam. The β-lactamases are excellent examples of ‘microevolution’ that led to ‘gain-of-function’ with extended substrate spectrum. The plasmid borne nature of these genes accentuates the problem of horizontal transfer of these resistance genes among related and un-related bacteria. Therefore it is important to understand the emergence of these enzyme variants.</p> <p><strong>Method: </strong>literatures were searched using the keywords ‘mutation’, ‘ESBL’, ‘β-lactamase’ on the servers like Google scholar and pubmed. The found literatures were reevaluated for any repetition. Unique literatures were then served as study subjects.</p> <p><strong>Results:</strong> These enzymes are serine hydrolases and utilize a host of conserved amino acids which though a coordinated sequence of events, catalyze the antibiotic inactivation. The active side serine residue catalyzes the nucleophilic attack and hydrolysis of beta lactam antibiotics. Critical mutations gathered in these proteins caused gain-of-function causing them to become more versatile.</p> PRIYANKA bhowmik, Rohan Dutta, Anurati Mandol, Subhas Samui, Nasrin Sultana Copyright (c)